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54gene raises $4.5M Seed Round to build world-first biobank for African DNA datasets

Milcah Lukhanyu by Milcah Lukhanyu
2 years ago
in Tech
12 min read
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VC-backed healthtech startup 54gene, a former YC and Google Launchpad cohort startup which wants to be the D.B.A. of Stack Diagnostics has raised a $4.5M seed round to build world-first biobank for African DNA datasets.

The investment was raised from Y Combinator, Fifty Years,Better Ventures, KdT Ventures, Hack VC and Techammer, among others.

The early-stage investment will allow the six-month old start-up to pioneer and build the world’s first African DNA biobank, install electronic data capture systems in the leading tertiary hospitals in Nigeria and expand its world-class teams both in the US and Nigeria, ahead of the company’s expansion plans on the continent.

According to Abasi Ene-Obong PhD, Founder and CEO of 54gene, “The genomic revolution has taken place everywhere except for Africa; home to more than 1 billion people, and the very birthplace of humankind. What many people don’t realize is how genetically diverse Africa is, and that Africans have married within their tribes for thousands of years, which makes our DNA ideal for studying loss-of-function type mutations that can be replicated into new drugs. We believe this will be done through partnering with pharmaceutical industry players to drive groundbreaking research and layering a data science capability on the data being collected. We believe this will be done through partnering with pharmaceutical industry players to drive groundbreaking research and layering a data science capability on the data being collected.”

As of 2018, only 2% of the data used in Genome-wide Association Studies [GWAS] were of African ancestry. 54gene is now positioned to build the largest database of genomic and phenotypic consented data of Africans. The unique data sets will be used exclusively for research; to proactively address the significant gap the genomics market currently poses for Africa, using African DNA to focus on drug discovery opportunities that will improve access.

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Following a successful pilot in three of Nigeria’s largest academic tertiary hospitals, the YC alumnus is strategically expanding its biobanking activities to 10 of the country’s academic tertiary hospitals. The biobank’s focus has also expanded from oncology to include cardiology, neurology, endocrinology and sickle cell disease. The company expects to secure 40,000 biobank samples by the end of this year and is working closely with research institutions on the continent, pharmaceutical companies, technology partners and healthcare regulators, to achieve this.

The global pharmaceutical industry is expected to reach $1.34 trillion by 2020. 54gene will focus its attention on Africa and the African Diaspora, charting new territory for the global pharma industry.

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Seth Bannon, Founding Partner at Fifty Years, “It’s a dirty secret that the world’s genomic datasets are overwhelmingly caucasian. By building datasets that are more inclusive, 54Gene will help democratize molecular medicine while unlocking insights that will lead to better therapeutics for everyone.”

Mack Healy, KDT says the subsequent diagnostic and therapeutic insights will be invaluable in the advancement of the quality of healthcare and well being of an increasingly large and underrepresented population.

“We’re thrilled to be working with Abasi and the team at 54Gene as they unlock the potential of the African genome to benefit global health and democratize access to molecular medicine. Abasi is the quintessential mission-driven founder we seek to back who is using breakthrough technology to solve a big problem,” added Wes Selke Better VC.

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It takes 10 to 15 years after an innovative drug has been launched in the US or Europe for it to get to Africa, 54gene believes that if it understands the genetic profile of diseases that are prevalent amongst Africans, it can deliver population health management strategies to people of African origin all over the world, helping equilibrate medical care for all.

“Technology will allow us to achieve this, at scale and we plan to reach some impressive and unique milestones in 2019,” Abasi concludes.

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Milcah Lukhanyu

Milcah Lukhanyu

Milcah Lukhanyu covers daily news briefs at TechMoran. She is the person who will probably read your press release and get the story out of it or totally trash it. Send tips to [email protected]

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